H04 · mRNA-LNP Full-Length

Stub hub. Details in STRC mRNA-LNP Strategy B Full-Length. State lives in frontmatter above.

next step

No fast compute-to-S path; keep as AAV maintenance/interim only unless new OHC-LNP tropism data reaches therapeutic population coverage.

Recent activity

const p = dv.page(dv.current().file.folder + "/log.md")
if (p && p.file.lists.length) dv.list(p.file.lists.slice(0, 5).map(l => l.text))
else dv.paragraph("_(no log entries)_")

• h04 log
• strc
• h04
• 2026-08-21 re-rank: tier B held, all scores held. lit_audit fixed → partial with 4 enumerated blockers (upstream PK/PD stays sourced; the dB OUTPUT layer is NOT-MODELABLE). Moderna INTerpath-001 readout carries no information about eff and moves nothing. → STRC Program Re-Rank 2026-08-21
• Outcome-chain disposition: NOT-MODELABLE. 0/8 executable calibration pairs grounded end-to-end. → STRC h04 Outcome Chain Disposition 2026-08-21

Connections

• [part-of] STRC Hypothesis Ranking
• [see-also] STRC mRNA-LNP Strategy B Full-Length