dock
SWISS-MODEL
Automated protein homology modeling server by SIB Swiss Institute of Bioinformatics. Builds 3D protein models based on evolutionary related structures.
What It Does
- Builds 3D protein models by homology to known experimental structures
- Template search across PDB
- Model quality estimation (GMQE, QMEANDisCo)
- Oligomeric state prediction
How to Use
Web Interface
- Go to https://swissmodel.expasy.org
- Paste protein sequence or UniProt ID
- Choose template or let auto-select
- Download resulting model (PDB format)
API
# Submit modeling job
curl -X POST https://swissmodel.expasy.org/automodel \
-H "Content-Type: application/json" \
-d '{"target_sequences": "MVLSPA...", "project_title": "STRC"}'Verified Status
VERIFIED — STRC has ZERO pre-computed homology models in SWISS-MODEL Repository (no experimental homolog in PDB). AlphaFold predictions are the only available 3D structures. SWISS-MODEL is NOT useful for STRC (no close experimental homolog in PDB). AlphaFold predictions generally superior for STRC.
STRC Research Usage
- Secondary validation of AlphaFold predictions
- Useful when experimental structures of homologs exist
Connections
- AlphaFold Database [see-also] — usually better for STRC
- AlphaFold 3 Server [see-also] — better for complexes
- UniProt [depends-on]