STRC h01 Phase 7I v52 Combined Boltz-2 Analysis 2026-04-26

Bridge note for the Phase 7I result that originally landed as an artifact summary. It keeps working notes linked into the durable phases/ graph while the raw analysis files stay under artifacts/phase7i_v52_combined/.

Headline: 12 paired v5.2 ligands split into 4 mutant-prefer, 5 WT-prefer, and 3 ties. The result falsifies a blanket “aq3 carrier implies mutant preference” rule and shifts the decision variable toward head-group class.