STRC Research

Tag: strc

370 items with this tag.

Apr 28, 2026
Tools
Apr 24, 2026
Concepts & Notes
- strc
- moc
Apr 24, 2026
Literature Audit
- strc
- moc
Apr 23, 2026
H04 · mRNA-LNP Full-Length
- strc
- h04
Apr 23, 2026
H06 · mRNA Therapy / RBM24
- strc
- h06
Apr 23, 2026
H07 · Prime Editing
- strc
- h07
Apr 23, 2026
H08 · ASO Exon Skipping
- strc
- h08
Apr 23, 2026
H10 · SpyCatcher Assembly
- strc
- h10
Apr 23, 2026
H11 · TECTA Chimera
- strc
- h11
Apr 23, 2026
H12 · Sonogenetic Proof
- strc
- h12
Apr 23, 2026
H13 · Programmable Recombinases
- strc
- h13
Apr 23, 2026
H14 · Protein Replacement
- strc
- h14
Apr 23, 2026
H15 · OTOA Paralog Rescue
- strc
- h15
Sep 10, 2026
Efficacy and safety of SENS-501, a dual-AAV otoferlin gene therapy, for DFNB9 congenital deafness.
Aug 21, 2026
STRC h04 Outcome Chain Disposition 2026-08-21
Aug 21, 2026
2026-08-21-digest
Aug 21, 2026
Choice of vector and surgical approach enables efficient cochlear gene transfer in nonhuman primate
Aug 21, 2026
Loss of Zbtb20 disrupts cochlear supporting cell differentiation and maturation and extends the postnatal hair cell regenerative window in mice.
Aug 21, 2026
Piezo channels in physical field therapy: From mechanotransduction mechanisms to bioelectromagnetic modulation and biomedical applications.
Aug 17, 2026
2026-08-17-digest
Aug 17, 2026
Piezoelectric shaping of radical mastoid cavity and dissection of ossified cochlea prior to cochlear implantation.
Aug 17, 2026
Acbd7 is essential for preserving hair cell-mediated auditory and vestibular function.
Aug 08, 2026
STRC-STRCP1 Locus Identity Gate
Aug 08, 2026
2026-08-08-digest
Aug 08, 2026
Precision correction of the GJB2 c.235delC mutation by prime editing in vitro.
Aug 08, 2026
Erratum: Efficacy and safety of SENS-501, a dual-AAV otoferlin gene therapy, for DFNB9 congenital deafness.
Aug 05, 2026
2026-08-05-digest
Aug 05, 2026
[Advances in research on the molecular mechanisms and gene therapy of hereditary hearing impairment].
Aug 05, 2026
Mechanotransduction in intervertebral disc degeneration: from compartment-specific sensors to translational frontiers.
Aug 05, 2026
Efficient and Safe Transduction of Cochlear Outer Hair Cells in Adult Mice with AAV2.7m8-Myo15.
Aug 05, 2026
Age outweighs route for AAV-PHP.eB transgene distribution via inner ear delivery.
Aug 05, 2026
From Static Scaffolds to Responsive Implants: 3D-Printed Field-Active Bioceramics for Adaptive Bone Regeneration.
Aug 05, 2026
Lunsotogene Parvec: First Approval.
Aug 05, 2026
Ca2+ regulation of PMCA2 calcium pump expression in hair cells of Tmc1 deafness mutants.
Jul 20, 2026
2026-07-20-digest
Jul 18, 2026
Restoration, Not Bypass: Otoferlin Gene Therapy and a New Era in Hearing Loss Treatment.
Jul 16, 2026
2026-07-16-digest
Jul 15, 2026
2026-07-15-digest
Jul 14, 2026
Advances in RNA delivery to extrahepatic tissues and cells.
Jul 13, 2026
In vivo-directed evolution identifies AAV-WM04 as a next-generation vector for potent and sustained hearing restoration in DFNB9.
Jul 11, 2026
2026-07-11-digest
Jul 10, 2026
2026-07-10-digest
Jul 10, 2026
PIP2-Tmie Interactions Drive Mammalian Hair Cell Slow Adaptation Independently of Myosin Motors
Jul 09, 2026
ATP8B1-TMEM30B Flippase Activity Maintains Stereocilia Lipid Asymmetry Required for Hearing
Jul 09, 2026
Spatiotemporal cellular landscape of the human utricle sensory epithelium
Jul 09, 2026
Rescue of stereocilia architecture and hearing function by AAV-CIB2 and AAV-CIB3 in a mouse model of recessive deafness DFNB48.
Jul 09, 2026
Connexin 30 mutation rescues high-frequency hearing, reduces gap junctional coupling and alters potassium currents in cochlear Deiters cells
Jul 04, 2026
2026-07-04-digest
Jul 03, 2026
Kv4, Kv2, and Kv3 currents shape intrinsic lateral olivocochlear excitability independent of hair cell dysfunction during development and ageing.
Jul 03, 2026
[Promising methods for sensorineural hearing loss treatment: Cellular technologies].
Jun 28, 2026
2026-06-28-digest
Jun 27, 2026
2026-06-27-digest
Jun 26, 2026
2026-06-26-digest
Jun 26, 2026
Re-administration of AAV-mediated gene therapy for OTOF-related deafness: a single-arm trial.
Jun 25, 2026
2026-06-25-digest
Jun 25, 2026
Clarin-1 mRNA expression in the central auditory system of Fischer Brown Norway rats.
Jun 24, 2026
Viral Infections and Neurodegenerative Diseases: Reinterpreting the Crosstalk Through a Dual-Role Lens.
Jun 23, 2026
2026-06-23-digest
Jun 22, 2026
Upregulation of ATP-purinergic P2x2 receptors in the cochlea over-amplifies hearing sensitivity leading to hyperacusis and attenuation by antagonists
Jun 20, 2026
2026-06-20-digest
Jun 16, 2026
2026-06-16-digest
Jun 16, 2026
Cryo-EM reveals a right-handed double-helix dimer architecture of PCDH15.
Jun 14, 2026
2026-06-14-digest
Jun 13, 2026
2026-06-13-digest
Jun 13, 2026
Enhancing Round Window Membrane Permeability for Inner Ear Drug Delivery: A Systematic Review.
Jun 13, 2026
Adenovirus-mediated co-regulation of Notch, FGF and BMP signaling pathways promotes the regeneration of cochlear hair cells in neonatal mice.
Jun 11, 2026
2026-06-11-digest
Jun 10, 2026
2026-06-10-digest
Jun 09, 2026
2026-06-09-digest
Jun 09, 2026
Otoprotective effect of MnTBAP in cisplatin-induced hearing loss
Jun 08, 2026
A Fungal-Derived Bioactive Resource for Cochlear Protection: Sanghuangporus sanghuang Extract Mitigates Acoustic Trauma through Nrf2/HO-1 Antioxidant Axis.
Jun 08, 2026
Conformational changes underlying electromechanical transduction in prestin resemble a transport transition in pendrin
Jun 07, 2026
2026-06-07-digest
Jun 06, 2026
Broadband amplification of organ of Corti vibrations in the mouse cochlear apex
Jun 05, 2026
2026-06-05-digest
Jun 04, 2026
Genomic and Epigenomic Advances in Hearing Loss: Molecular Mechanisms, Diagnostics, and Emerging Therapies.
Jun 03, 2026
Tonotopic specialization of MYO7A isoforms in auditory hair cells.
Jun 02, 2026
2026-06-02-digest
May 31, 2026
The Genetic Causes of Auditory Neuropathy: A Systematic Review.
May 30, 2026
Peripheral phoneme encoding and discrimination in aging and hearing impairment
May 29, 2026
2026-05-29-digest
May 28, 2026
TrkB activation mitigates blast-induced cochlear pathology and promotes auditory recovery in a compressed-air blast model.
May 28, 2026
Alzheimer disease beta-amyloid pathology accelerates age-related hearing loss: evidence from AppNL-F 'knock-in' mice
May 27, 2026
Connexin 26 in Hearing Health and Disease: StructuralFoundations, Mutation Mechanisms, and Therapeutic Perspectives.
May 21, 2026
2026-05-21-digest
May 20, 2026
2026-05-20-digest
May 19, 2026
FDA Approval of the Congenital OTOF Gene Therapy Otarmeni Reshapes the Future of Hearing Care.
May 18, 2026
Discovery of a Novel Non-MET-Mediated Otoprotective Compound Against Aminoglycoside-Induced Ototoxicity
May 16, 2026
2026-05-16-digest
May 14, 2026
2026-05-14-digest
May 13, 2026
2026-05-13-digest
May 12, 2026
Vault Lint 2026-05-12
May 12, 2026
[Sensorineural hearing loss and autoimmune diseases: relevant view on the problem].
May 11, 2026
2026-05-11-digest
May 10, 2026
2026-05-10-digest
May 09, 2026
2026-05-09-digest
May 08, 2026
2026-05-08-digest
May 07, 2026
2026-05-07-digest
May 06, 2026
2026-05-06-digest
May 02, 2026
2026-05-02-digest
Apr 29, 2026
2026-04-29-digest
Apr 29, 2026
Mesenchymal vs. induced pluripotent stem cells: potential for spiral ganglion neuron regeneration in auditory neuropathy.
Apr 29, 2026
Research Progress of MYO6 Variant-Associated Hereditary Hearing Loss.
Apr 28, 2026
2026-04-28-digest
Apr 28, 2026
overnight-research
Apr 27, 2026
phase9b_mmpbsa_smoke
Apr 27, 2026
STRC h01 Phase 9b Min-Relax Multi-Frame MM-GBSA Smoke 2026-04-27
Apr 27, 2026
STRC h09 Phase 4k Fibril Actin Geometry 2026-04-27
Apr 27, 2026
STRC h09 Phase 4m Kd Mono Soft Floor Result 2026-04-27
Apr 27, 2026
STRC h09 Phase 4o AF-M Nanobody Method Transfer 2026-04-27
Apr 27, 2026
STRC h09 Phase 4p Boltz WH2 Orthogonal Controls 2026-04-27
Apr 27, 2026
STRC h26 Phase 1d AF3 Final 2026-04-27
Apr 27, 2026
STRC AF3 Interface Triage Protocol
Apr 27, 2026
Vina
Apr 27, 2026
2026-04-27-digest
Apr 27, 2026
In silico discovery of nanobody binders to a G-protein coupled receptor using AlphaFold-Multimer
Apr 27, 2026
Repertoire-scale antibody structural prediction informs therapeutic design
Apr 27, 2026
AmberTools
Apr 27, 2026
GROMACS
- strc
- tool
- md
- gromacs
Apr 27, 2026
MRGPRX2 AF-M screen
Apr 27, 2026
gmx_MMPBSA
Apr 26, 2026
Phase 8h-lite · Light computational evidence package for H01
Apr 26, 2026
Phase 8h-lite #1 · K1141 pocket druggability profile
Apr 26, 2026
Phase 8h-lite #2 · RWM permeability prediction for lead candidate
Apr 26, 2026
Phase 8h-lite #3 · Off-target selectivity charge proxy (inconclusive light)
Apr 26, 2026
Phase 8h-lite #4 · Lead-pose ensemble stability vs K1141 across Phase 5d
Apr 26, 2026
Phase 8h-lite #5 · Tanimoto vs known cochlear ototoxins
Apr 26, 2026
Phase 8h-lite #6 · Tier-1 RWM permeability + Tanimoto refresh after Phase 7I lead pivot
Apr 26, 2026
Phase 8h-lite #7 · Cochlear-compartment PBPK ODE
Apr 26, 2026
Phase 8h-lite #8 · K1141 pocket vs stereocilin-partner interface map
Apr 26, 2026
STRC E1659A QC Rate-Limiting Step Lit Gap-Map
Apr 26, 2026
STRC h01 Phase 5e v5.3 Mut Ensemble Dock 2026-04-26
Apr 26, 2026
STRC h01 Phase 5e-v2 v5.2 Shortlist Vina vs tauRAMD 2026-04-26
Apr 26, 2026
STRC h01 Phase 5m TRPM4 Cross-Target tauRAMD 2026-04-26
Apr 26, 2026
STRC h01 Phase 5q v5.3 Acyl Sulfonamide Boltz-2 + Vina Consensus 2026-04-26
Apr 26, 2026
STRC h01 Phase 5q v5.3 STRC Within-Target tauRAMD 2026-04-26
Apr 26, 2026
STRC h01 Phase 7I v52 Combined Boltz-2 Analysis 2026-04-26
Apr 26, 2026
STRC h01 Phase 8c v5.3 ADMET-AI Triage 2026-04-26
Apr 26, 2026
STRC h01 Phase 8h-lite · Light Computational Evidence Package 2026-04-26
Apr 26, 2026
STRC h01 State Audit 2026-04-26
Apr 26, 2026
STRC h09 PKPD Window Calc
Apr 26, 2026
STRC h09 Phase 4b AF3 Robustness Gate 2026-04-26
Apr 26, 2026
STRC h09 Phase 4m Kd Mono Soft Floor Pre-Registration 2026-04-26
Apr 26, 2026
Ataluren Reporter-Stabilization Trap
Apr 26, 2026
ELX-02 In Vitro Clinical PBPK Disconnect
Apr 26, 2026
Givinostat mARC1 2 Hydroxamate Bypass
Apr 26, 2026
Hydroxamic Acid Divalent Cation Liability
Apr 26, 2026
Migalastat Dosing-Cycle Principle
Apr 26, 2026
Pharmacochaperone Residence Time Criterion
Apr 26, 2026
SLC26A4 H723R Pharmacochaperone Precedent
Apr 26, 2026
STRC K1141 Fragment Construct Strategy
Apr 26, 2026
Tafamidis Kinetic-Stabilization Paradigm
Apr 26, 2026
OpenMM
Apr 26, 2026
RAMD-OpenMM
Apr 26, 2026
RDKit
Apr 26, 2026
fpocket
Apr 25, 2026
STRC h01 Parameter Provenance Audit 2026-04-25
Apr 25, 2026
STRC h01 Phase 5k-WT Matched Ensemble APBS 2026-04-25
Apr 25, 2026
STRC h01 Phase 7H AFS Allowlist Block 2026-04-25
Apr 25, 2026
STRC h01 Phase 7H Boltz-2 NSAID Validation 2026-04-25
Apr 25, 2026
STRC h01 Phase 8d 8e 8f v5.2 Library Design 2026-04-25
Apr 25, 2026
STRC h03 Parameter Provenance Audit 2026-04-25
Apr 25, 2026
2026-04-25 STRC Vault Split Metrics Drop
Apr 25, 2026
Actin Polymerization Kinetics Reference Table
Apr 25, 2026
Amino Acid Physicochemical Distance Matrix Grantham Modified
Apr 25, 2026
Arp2 3 Complex Two-NPF Activation Requirement
Apr 25, 2026
Capping Protein Dissociation Half-Life
Apr 25, 2026
Cofilin Filament Twist Geometry Change
Apr 25, 2026
Cofilin Severing Substoichiometric Optimum
Apr 25, 2026
De Novo Design Software Scoring Strategy Catalog
Apr 25, 2026
Flat-Histogram Reweighting Reference Table
Apr 25, 2026
Fragment Additivity Assumption and Superadditivity
Apr 25, 2026
Hair Cell Biophysical Reference Table
Apr 25, 2026
Ligand Efficiency Metrics Catalog
Apr 25, 2026
Lipinski Rule of Fives vs Congreve Rule of Threes Reference Table
Apr 25, 2026
MFEP Two-Stage Strategies Table
- strc
- data
- p0
- free-energy
- fep
- mfep
- h01
Apr 25, 2026
OHC Bundle Damping Cartagena 2019
Apr 25, 2026
OHC Bundle Geometry Apical Mouse Cartagena 2019
Apr 25, 2026
Phase Space Overlap and FEP Sampling
Apr 25, 2026
Recipe — ABF Adaptive Biasing Force Algorithm
- strc
- recipe
- p1
- free-energy
- ti
- abf
- pmf
- h09
- h26
Apr 25, 2026
Recipe — Ant Colony Optimization for Peptide Sequence Design
Apr 25, 2026
Recipe — Bennett Acceptance Ratio Estimator
- strc
- recipe
- p1
- free-energy
- fep
- bar
- estimator
- h01
- h26
Apr 25, 2026
Recipe — FEP Point-Mutation Algorithm
Apr 25, 2026
Recipe — Fragment Library Filtering Pipeline
Apr 25, 2026
Recipe — Fragment Optimization Linking Merging Growing
Apr 25, 2026
Recipe — LRA Method for pKa Shift Calculation
Apr 25, 2026
Recipe — Noncontact FM-AFM Hair Bundle Mechanics
Apr 25, 2026
Recipe — Profilin Thymosin-β4 Monomer Pool Partitioning
Apr 25, 2026
Recipe — Receptor-Based Scoring Function Selection
Apr 25, 2026
Recipe — Short WH2 Actin Binder Design
- strc
- recipe
- p1
- wh2
- actin
- h09
Apr 25, 2026
Recipe — Soft-Core Potential for Alchemical End Points
Apr 25, 2026
Recipe — TMSB4X-Buffered Free G-actin Pool Estimation
Apr 25, 2026
Recipe — Therapeutic Peptide Stability Modifications
Apr 25, 2026
Short vs Long WH2 Domain Classification
- strc
- concept
- p2
- wh2
- actin
Apr 25, 2026
Single-Topology vs Dual-Topology Alchemical Paradigms
Apr 25, 2026
Stereocilia Actin Cytoskeleton
Apr 25, 2026
TMSB4X Actin Buffering Stoichiometry Hair vs Supporting Cells
Apr 25, 2026
Tandem WH2 Filament Nucleation Mechanism
Apr 25, 2026
Tropomodulin Pointed End Cap Mechanism
Apr 25, 2026
h26 Gate Pilot — PeptAI Discipline Import 2026-04-25
Apr 25, 2026
aav-cochlear-delivery
Apr 25, 2026
calcium-oscillation
Apr 25, 2026
free-energy-methods
Apr 25, 2026
STRC Sources & Books MOC
Apr 25, 2026
1997-owens-pde4a-kinetics
- strc
- h05
- paper
- pde4
- camp
- kinetics
- cAMP
Apr 25, 2026
1998-lumpkin-hudspeth-stereocilia-calcium-regulation
Apr 25, 2026
1998-santalucia-unified-nearest-neighbor-dna
Apr 25, 2026
1998-yamoah-pmca-stereocilia-extrusion
Apr 25, 2026
2003-houslay-adams-pde4-review
- strc
- h05
- paper
- pde4
- camp
- kinetics
- cAMP
Apr 25, 2026
2004-matsuda-prestin-n-glycosylation
Apr 25, 2026
2005-hackney-calcium-buffering-proteins
Apr 25, 2026
2007-chipot-free-energy-calculations-book
- strc
- paper
- free-energy
- md
- fep
- ti
- abf
- mm-pbsa
- lra
- pka
- methods
Apr 25, 2026
2009-halgren-sitemap-druggability
Apr 25, 2026
2010-beurg-calcium-balance-ohc
Apr 25, 2026
2010-rajagopalan-prestin-glycosylation-jaro
Apr 25, 2026
2011-chao-camkii-holoenzyme-structure
Apr 25, 2026
2011-schwanhauser-mammalian-gene-expression-control
Apr 25, 2026
2012-zakeri-spycatcher-spytag-pnas
Apr 25, 2026
2012-zhang-stereocilia-protein-turnover
Apr 25, 2026
2014-schneider-de-novo-molecular-design-book
Apr 25, 2026
2015-genheden-ryde-mmpbsa-mmpgbsa-review
Apr 25, 2026
2019-anzalone-prime-editing-nature
Apr 25, 2026
2021-eberhardt-autodock-vina-1-2
Apr 25, 2026
2022-zhi-dual-aav-split-pe-retina
Apr 25, 2026
2024-davis-dual-aav-split-prime-editor-brain
Apr 25, 2026
2024-hartig-stereocilia-elongation-protein-stability
Apr 25, 2026
2025-roman-prime-editing-rbm20-cardiomyocytes
Apr 25, 2026
2026-04-25-ashmore-1987-ohc-electromotility-jphysiol
Apr 25, 2026
2026-04-25-gao-2014-organ-corti-oct-vibration
Apr 25, 2026
2026-04-25-gavara-2009-tm-collagen-anisotropy-afm
Apr 25, 2026
2026-04-25-gentet-2000-specific-membrane-capacitance-neurons
Apr 25, 2026
2026-04-25-ghaffari-2007-tm-traveling-wave-pnas
Apr 25, 2026
2026-04-25-gueta-2008-tm-anisotropy-stereocilia-deflection
Apr 25, 2026
2026-04-25-hu-2021-pvdftrfe-insitu-poling-frontiers-energy
Apr 25, 2026
Investigation of the Effects of Cadherin 23 and Oncomodulin on Early Progressive Hearing Loss Using a New Oncomodulin Mouse Model.
Apr 25, 2026
2026-04-25-masaki-2009-tm-col11a2-anisotropy
Apr 25, 2026
2026-04-25-ren-2002-bm-traveling-wave-pnas
Apr 25, 2026
2026-04-25-santos-sacchi-1991-prestin-nlc-voltage
Apr 25, 2026
2026-04-25-shoelson-2004-tm-elasticity-inhomogeneity-biophysj
Apr 25, 2026
2026-04-25-teudt-2014-tm-bm-stiffness-cba-mouse
Apr 25, 2026
2026-sun-rbm24-alternative-splicing-cochlear
Apr 25, 2026
Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bu
Apr 25, 2026
Single-cell proteomics reveals changes in expression during hair-cell developmen
Apr 25, 2026
STRC Literature Log
Apr 24, 2026
STRC h01 Phase 3c v4 Fragment-Grow Delivery 2026-04-24
Apr 24, 2026
STRC h01 Phase 4c-v3b WT Decoy on v3b YELLOW 2026-04-24
Apr 24, 2026
STRC h01 Phase 4d K1141A Double-Mutant Decoy 2026-04-24
Apr 24, 2026
STRC h01 Phase 4i APBS Pose-Transplant Rescore 2026-04-24
Apr 24, 2026
STRC h01 Phase 5c-Mutant Cryptic Pocket Scan 2026-04-24
Apr 24, 2026
STRC h01 Phase 5j APBS WT vs Mutant Pocket Electrostatics 2026-04-24
Apr 24, 2026
STRC h01 Phase 5k Ensemble APBS on Phase 5d Mutant MD 2026-04-24
Apr 24, 2026
STRC h01 Phase 6c hERG Extension 2026-04-24
Apr 24, 2026
STRC h01 Phase 7 ADMET-AI Triage 2026-04-24
Apr 24, 2026
STRC h01 Phase 7H AF3 Protein-Ligand Validation 2026-04-24
Apr 24, 2026
STRC h01 Phase 8c v5 ADMET-AI Triage 2026-04-24
Apr 24, 2026
STRC AF3 Ultra-Mini Multimer Validation
Apr 24, 2026
STRC h03 B8 Enhancer Bp Resolved 2026-04-24
Apr 24, 2026
log
- strc
- h06
Apr 24, 2026
log
- strc
- h08
Apr 24, 2026
log
- strc
- h09
Apr 24, 2026
STRC Horizontal Top Connector Hydrogel Hypothesis
Apr 24, 2026
STRC Hydrogel Phase 4d F-actin Bundling Model
Apr 24, 2026
log
- strc
- h10
Apr 24, 2026
log
- strc
- h11
Apr 24, 2026
log
- strc
- h12
Apr 24, 2026
log
- strc
- h13
Apr 24, 2026
log
- strc
- h14
Apr 24, 2026
log
- strc
- h15
Apr 24, 2026
Actin Treadmilling Stereocilia
Apr 24, 2026
Gating Spring Frequency Tuning
Apr 24, 2026
Hair Bundle Stiffness Decomposition
Apr 24, 2026
Research Artifact Retention Policy
Apr 24, 2026
STRC ABR Transfer Function Model
Apr 24, 2026
STRC AF3 Static Pocket Blindness to Loop Dynamics
Apr 24, 2026
STRC E1 Conservation and NMD Motifs
Apr 24, 2026
STRC Rescue Threshold
Apr 24, 2026
STRCP1
Apr 24, 2026
Stereocilin
Apr 24, 2026
1981-jencks-binding-energies-additivity-pnas
Apr 24, 2026
1998-kramer-karpen-polymer-ligand-dimers-nature
Apr 24, 2026
1998-mammen-polyvalent-interactions-angew
Apr 24, 2026
2014-choi-wpre3-aav-expression-cassette
Apr 24, 2026
2024-hu-myo15-promoter-engineering
- strc
- paper
- aav
- myo15
- promoter
- hair-cell
- h03
- ohc
- dfnb9
Apr 24, 2026
2024-lv-aav1-otof-lancet-trial
Apr 24, 2026
2025-zhao-arbiter-b8-enhancer-ohc
- strc
- paper
- aav
- enhancer
- ohc
- b8
- arbiter
- slc26a5
- prestin
- h03
Apr 24, 2026
ADMET-AI
Apr 24, 2026
APBS
Apr 23, 2026
STRC h09 Phase 4e_v2 Blend Scaffold
Apr 23, 2026
STRC h10 h11 Parameter Provenance Audit 2026-04-23
Apr 23, 2026
actin-kinetics
Apr 23, 2026
avidity-and-dimers
Apr 23, 2026
cochlear-pkpd
Apr 23, 2026
2026-04-23-digest
Apr 23, 2026
pharmacochaperone
Apr 23, 2026
piezoelectric-materials
Apr 23, 2026
rada16-geometry
Apr 23, 2026
stereocilia-mechanics
Apr 23, 2026
strc-tmem145-interactions
Apr 23, 2026
tectorial-membrane
Apr 23, 2026
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
Apr 23, 2026
Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B
Apr 23, 2026
Calcium oscillations increase the efficiency and specificity of gene expression
Apr 23, 2026
A large-conductance calcium-selective mechanotransducer channel in mammalian cochlear hair cells
Apr 23, 2026
Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains
Apr 23, 2026
Distinct mechanisms of calmodulin binding and regulation of adenylyl cyclases 1 and 8
Apr 23, 2026
The physiology of mechanoelectrical transduction channels in hearing
Apr 23, 2026
Actin-bound structures of Wiskott–Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
- strc
- paper
- actin
- wh2
- wasp
- biophysics
- h09
Apr 23, 2026
The WH2 Domain and Actin Nucleation: Necessary but Insufficient
Apr 23, 2026
Multifunctionality of the β-thymosin/WH2 module: G-actin sequestration, actin filament growth, nucleation, and severing
Apr 23, 2026
Single-cell proteomics reveals changes in expression during hair-cell development
Apr 23, 2026
Rate constants for the reactions of ATP- and ADP-actin with the ends of actin filaments
Apr 23, 2026
Actin and Actin-Binding Proteins
Apr 23, 2026
The organization of actin filaments in the stereocilia of cochlear hair cells
Apr 22, 2026
STRC Pharmacochaperone Phase 4f Interface Rescue SMOKE
Apr 22, 2026
STRC Pharmacochaperone Phase 4g Repurpose Screen
Apr 21, 2026
STRC Research Monitor Pipeline
Apr 21, 2026
Alternative splicing of the Rbm24 gene is essential for cochlear hair cell stereocilia integrity and hearing function in mice
Apr 20, 2026
STRC TMEM145 GOLD Domain Interaction
Apr 20, 2026
STRC AC1-CREB Parameter Robustness
Apr 20, 2026
STRC RBM24 Exon Splicing Quantification
Apr 15, 2026
Cochlear AAV Inflammation 2025
Apr 15, 2026
Extracellular Vesicle Delivery Cochlea 2024
Apr 15, 2026
New AAV Capsids 2025 Cochlear
Apr 15, 2026
OTOF Clinical Trials 2025 Dual-AAV Validation
Apr 15, 2026
Programmable Recombinases Hearing Loss
Apr 08, 2026
ASGCT Gene Therapy Database
Apr 08, 2026
AlphaFold 3 Server
Apr 08, 2026
AlphaFold Database
Apr 08, 2026
Caduceus
Apr 08, 2026
ClinGen
Apr 08, 2026
ClinicalTrials.gov
Apr 08, 2026
Clustal Omega
Apr 08, 2026
DNABERT-2
Apr 08, 2026
Deafness Variation Database
Apr 08, 2026
ESMFold
Apr 08, 2026
Evo — Evo 2
Apr 08, 2026
Hereditary Hearing Loss Homepage
Apr 08, 2026
HyenaDNA
Apr 08, 2026
IUPred3
Apr 08, 2026
InterVar
Apr 08, 2026
Mol Star Viewer
Apr 08, 2026
NetGPI
Apr 08, 2026
NetNGlyc
Apr 08, 2026
Nucleotide Transformer (NTv3)
Apr 08, 2026
OMIM
Apr 08, 2026
OrthoDB
Apr 08, 2026
PubMed
Apr 08, 2026
PyMOL
Apr 08, 2026
SWISS-MODEL
Apr 08, 2026
SignalP
Apr 08, 2026
UCSC Genome Browser
Apr 08, 2026
UniProt
Apr 08, 2026
VarSome
Apr 08, 2026
dbNSFP
Apr 08, 2026
variant tools (vtools)
Mar 31, 2026
TMEM145 is a principal component of outer hair cell stereocilia
Mar 12, 2026
Capsid-engineered AAV vector overcomes a key intracellular barrier and efficiently transduces spiral ganglion neurons in adult mice.
Sep 27, 2021
Cochlear Size Assessment Predicts Scala Tympani Volume and Electrode Insertion Force — Implications in Robotic Assisted Cochlear Implant Surgery
Jun 01, 2021
Clinical Use of the Self-Assembling Peptide RADA16: A Review of Current and Future Trends in Biomedicine
Feb 20, 2019
Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics
Mar 01, 2018
Pharmacokinetic principles in the inner ear: Influence of drug properties on intratympanic applications
Oct 01, 2016
Human Cochlear Hydrodynamics: A High-Resolution μCT-Based Finite Element Study
Aug 01, 2015
Perilymph Kinetics of FITC-Dextran Reveals Homeostasis Dominated by the Cochlear Aqueduct and Cerebrospinal Fluid
Apr 01, 2009
Proteomics Analysis of Perilymph and Cerebrospinal Fluid in Mouse
Jun 14, 2005
Dynamic reassembly of peptide RADA16 nanofiber scaffold
Oct 01, 2003
Fabrication of novel biomaterials through molecular self-assembly
Nov 23, 2001
Self-assembly and mineralization of peptide-amphiphile nanofibers
Apr 01, 2001
Quantification of solute entry into cochlear perilymph through the round window membrane
Jun 06, 2000
Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds
Apr 15, 1993
Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane

Created with Quartz v4.5.2 © 2026

STRC marketing
Egor Lyfar
Contact