STRC Research

Tag: hair-cell

58 items with this tag.

Sep 10, 2026
Efficacy and safety of SENS-501, a dual-AAV otoferlin gene therapy, for DFNB9 congenital deafness.
Aug 21, 2026
Loss of Zbtb20 disrupts cochlear supporting cell differentiation and maturation and extends the postnatal hair cell regenerative window in mice.
Aug 17, 2026
Acbd7 is essential for preserving hair cell-mediated auditory and vestibular function.
Aug 05, 2026
[Advances in research on the molecular mechanisms and gene therapy of hereditary hearing impairment].
Aug 05, 2026
Efficient and Safe Transduction of Cochlear Outer Hair Cells in Adult Mice with AAV2.7m8-Myo15.
Aug 05, 2026
Age outweighs route for AAV-PHP.eB transgene distribution via inner ear delivery.
Aug 05, 2026
Lunsotogene Parvec: First Approval.
Aug 05, 2026
Ca2+ regulation of PMCA2 calcium pump expression in hair cells of Tmc1 deafness mutants.
Jul 13, 2026
In vivo-directed evolution identifies AAV-WM04 as a next-generation vector for potent and sustained hearing restoration in DFNB9.
Jul 10, 2026
PIP2-Tmie Interactions Drive Mammalian Hair Cell Slow Adaptation Independently of Myosin Motors
Jul 09, 2026
ATP8B1-TMEM30B Flippase Activity Maintains Stereocilia Lipid Asymmetry Required for Hearing
Jul 09, 2026
Spatiotemporal cellular landscape of the human utricle sensory epithelium
Jul 09, 2026
Connexin 30 mutation rescues high-frequency hearing, reduces gap junctional coupling and alters potassium currents in cochlear Deiters cells
Jul 03, 2026
Kv4, Kv2, and Kv3 currents shape intrinsic lateral olivocochlear excitability independent of hair cell dysfunction during development and ageing.
Jul 03, 2026
[Promising methods for sensorineural hearing loss treatment: Cellular technologies].
Jun 25, 2026
Clarin-1 mRNA expression in the central auditory system of Fischer Brown Norway rats.
Jun 22, 2026
Upregulation of ATP-purinergic P2x2 receptors in the cochlea over-amplifies hearing sensitivity leading to hyperacusis and attenuation by antagonists
Jun 16, 2026
Cryo-EM reveals a right-handed double-helix dimer architecture of PCDH15.
Jun 13, 2026
Adenovirus-mediated co-regulation of Notch, FGF and BMP signaling pathways promotes the regeneration of cochlear hair cells in neonatal mice.
Jun 09, 2026
Otoprotective effect of MnTBAP in cisplatin-induced hearing loss
Jun 08, 2026
A Fungal-Derived Bioactive Resource for Cochlear Protection: Sanghuangporus sanghuang Extract Mitigates Acoustic Trauma through Nrf2/HO-1 Antioxidant Axis.
Jun 08, 2026
Conformational changes underlying electromechanical transduction in prestin resemble a transport transition in pendrin
Jun 06, 2026
Broadband amplification of organ of Corti vibrations in the mouse cochlear apex
Jun 04, 2026
Genomic and Epigenomic Advances in Hearing Loss: Molecular Mechanisms, Diagnostics, and Emerging Therapies.
Jun 03, 2026
Tonotopic specialization of MYO7A isoforms in auditory hair cells.
May 31, 2026
The Genetic Causes of Auditory Neuropathy: A Systematic Review.
May 30, 2026
Peripheral phoneme encoding and discrimination in aging and hearing impairment
May 28, 2026
TrkB activation mitigates blast-induced cochlear pathology and promotes auditory recovery in a compressed-air blast model.
May 28, 2026
Alzheimer disease beta-amyloid pathology accelerates age-related hearing loss: evidence from AppNL-F 'knock-in' mice
May 27, 2026
Connexin 26 in Hearing Health and Disease: StructuralFoundations, Mutation Mechanisms, and Therapeutic Perspectives.
May 18, 2026
Discovery of a Novel Non-MET-Mediated Otoprotective Compound Against Aminoglycoside-Induced Ototoxicity
May 08, 2026
Differentiating the Physiological Signatures of Cochlear Synaptopathy and Inner Hair Cell Damage in a Chinchilla Model
- cochlea
- hair-cell
May 07, 2026
A Newly Identified Role of the Tectorial Membrane in Aminoglycoside Ototoxicity
May 06, 2026
Notch-driven asymmetry dictates hair cell behavior via a fate-specific kinase
- hair-cell
May 05, 2026
Regulation of Tmem30b-mediated apical membrane homeostasis in auditory outer hair cells is critical for hearing.
May 05, 2026
Estrogen-related receptor gamma is required for normal auditory innervation and is essential for hearing.
Apr 29, 2026
Mesenchymal vs. induced pluripotent stem cells: potential for spiral ganglion neuron regeneration in auditory neuropathy.
Apr 29, 2026
Research Progress of MYO6 Variant-Associated Hereditary Hearing Loss.
Apr 27, 2026
Transient disappearance of otoacoustic emissions after conventional hearing aid use in OTOF-related auditory neuropathy.
- hearing-loss
- hair-cell
Apr 25, 2026
Hair Cell Biophysical Reference Table
Apr 25, 2026
Recipe — TMSB4X-Buffered Free G-actin Pool Estimation
Apr 25, 2026
Stereocilia Actin Cytoskeleton
Apr 25, 2026
TMSB4X Actin Buffering Stoichiometry Hair vs Supporting Cells
Apr 25, 2026
WH2 Domain Actin Nucleation
Apr 25, 2026
1998-lumpkin-hudspeth-stereocilia-calcium-regulation
Apr 25, 2026
1998-yamoah-pmca-stereocilia-extrusion
Apr 25, 2026
2005-hackney-calcium-buffering-proteins
Apr 25, 2026
2010-beurg-calcium-balance-ohc
Apr 25, 2026
2012-zhang-stereocilia-protein-turnover
Apr 25, 2026
2024-hartig-stereocilia-elongation-protein-stability
Apr 25, 2026
Investigation of the Effects of Cadherin 23 and Oncomodulin on Early Progressive Hearing Loss Using a New Oncomodulin Mouse Model.
Apr 25, 2026
2026-sun-rbm24-alternative-splicing-cochlear
Apr 24, 2026
2024-hu-myo15-promoter-engineering
- strc
- paper
- aav
- myo15
- promoter
- hair-cell
- h03
- ohc
- dfnb9
Apr 24, 2026
The dual molecular identity of vestibular kinocilia bridges structural and functional traits of primary and motile cilia.
Apr 23, 2026
The physiology of mechanoelectrical transduction channels in hearing
Apr 23, 2026
Single-cell proteomics reveals changes in expression during hair-cell development
Apr 21, 2026
Alternative splicing of the Rbm24 gene is essential for cochlear hair cell stereocilia integrity and hearing function in mice
Mar 04, 2026
Cryo-EM reveals a right-handed double-helix dimer architecture of PCDH15 critical for mechanotransduction

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