STRC Research

Tag: gene-therapy

43 items with this tag.

Sep 10, 2026
Efficacy and safety of SENS-501, a dual-AAV otoferlin gene therapy, for DFNB9 congenital deafness.
Aug 08, 2026
Precision correction of the GJB2 c.235delC mutation by prime editing in vitro.
Aug 08, 2026
Erratum: Efficacy and safety of SENS-501, a dual-AAV otoferlin gene therapy, for DFNB9 congenital deafness.
Aug 05, 2026
[Advances in research on the molecular mechanisms and gene therapy of hereditary hearing impairment].
Aug 05, 2026
Efficient and Safe Transduction of Cochlear Outer Hair Cells in Adult Mice with AAV2.7m8-Myo15.
Aug 05, 2026
Age outweighs route for AAV-PHP.eB transgene distribution via inner ear delivery.
Jul 18, 2026
Restoration, Not Bypass: Otoferlin Gene Therapy and a New Era in Hearing Loss Treatment.
Jul 13, 2026
In vivo-directed evolution identifies AAV-WM04 as a next-generation vector for potent and sustained hearing restoration in DFNB9.
Jul 09, 2026
Rescue of stereocilia architecture and hearing function by AAV-CIB2 and AAV-CIB3 in a mouse model of recessive deafness DFNB48.
Jul 03, 2026
[Promising methods for sensorineural hearing loss treatment: Cellular technologies].
Jun 26, 2026
Re-administration of AAV-mediated gene therapy for OTOF-related deafness: a single-arm trial.
Jun 25, 2026
Clarin-1 mRNA expression in the central auditory system of Fischer Brown Norway rats.
Jun 24, 2026
Viral Infections and Neurodegenerative Diseases: Reinterpreting the Crosstalk Through a Dual-Role Lens.
Jun 13, 2026
Enhancing Round Window Membrane Permeability for Inner Ear Drug Delivery: A Systematic Review.
Jun 13, 2026
Adenovirus-mediated co-regulation of Notch, FGF and BMP signaling pathways promotes the regeneration of cochlear hair cells in neonatal mice.
May 31, 2026
The Genetic Causes of Auditory Neuropathy: A Systematic Review.
May 27, 2026
Connexin 26 in Hearing Health and Disease: StructuralFoundations, Mutation Mechanisms, and Therapeutic Perspectives.
May 19, 2026
FDA Approval of the Congenital OTOF Gene Therapy Otarmeni Reshapes the Future of Hearing Care.
May 12, 2026
[Sensorineural hearing loss and autoimmune diseases: relevant view on the problem].
Apr 29, 2026
Adenoviral-mediated gene transfer into the scala media of the mouse cochlea in vivo.
Apr 29, 2026
Research Progress of MYO6 Variant-Associated Hereditary Hearing Loss.
Apr 25, 2026
ARBITER Workflow for Cochlear Enhancer Discovery
Apr 25, 2026
Cochlear Drug Delivery Gradients
Apr 25, 2026
OHC-Specific Gene Delivery
Apr 25, 2026
Round Window Membrane Permeability
Apr 25, 2026
aav-cochlear-delivery
Apr 25, 2026
ARBITER — Deciphering Enhancers of Hearing Loss Genes — Zhao et al. 2025
Apr 22, 2026
Multicentre gene therapy for OTOF-related deafness followed up to 2.5 years.
Apr 20, 2026
STRC TMEM145 GOLD Domain Interaction
Apr 20, 2026
STRC RBM24 Exon Splicing Quantification
Apr 15, 2026
Cochlear AAV Inflammation 2025
Apr 15, 2026
Extracellular Vesicle Delivery Cochlea 2024
Apr 15, 2026
New AAV Capsids 2025 Cochlear
Apr 15, 2026
OTOF Clinical Trials 2025 Dual-AAV Validation
Apr 15, 2026
Programmable Recombinases Hearing Loss
Apr 14, 2026
Gene Therapy for Infants and Children With Otoferlin-Related Auditory Neuropathy Spectrum Disorder
Apr 14, 2026
Generation of human induced pluripotent stem cell lines from a patient with OTOF-related deafness and a carrier relative
Apr 08, 2026
Focused ultrasound mediated gene therapy for glioblastoma: A preclinical in vivo systematic review and meta-analysis
Apr 08, 2026
ASGCT Gene Therapy Database
Apr 08, 2026
ClinicalTrials.gov
Mar 25, 2026
Exploring Embryonic and Postnatal Gene Therapy Approaches for GJB2-Related Deafness: A Scoping Review.
Mar 12, 2026
Capsid-engineered AAV vector overcomes a key intracellular barrier and efficiently transduces spiral ganglion neurons in adult mice.
Feb 17, 2026
Postnatal Slc26a4 gene therapy improves hearing and structural integrity in a hereditary hearing loss model

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