Caduceus

Genomic language model leveraging the Mamba architecture with reverse-complement equivariance.

Key Info

• URL: https://github.com/kuleshov-group/caduceus
• Category: Emerging AI
• API: Yes
• Free: Free
• ACMG Relevance: PP3

Why It Matters

Employs state-space models to radically improve long-range variant-effect prediction efficiency compared to standard memory-heavy attention mechanisms.

STRC Research Usage

Documented. Requires local installation or specialized access.

Connections

30|- [[STRC Gene]] [about]

STRC E1659A Results

Not tested - local model. Bidirectional DNA language model. Tested: 2026-04-08