Stub hub. Details in STRC mRNA Therapy Hypothesis. State lives in frontmatter above.
next step
No fast compute-to-S path; needs primary OHC RBM24 titration or Sun 2026 quantification before another model can change tier.
Recent activity
const p = dv.page(dv.current().file.folder + "/log.md")
if (p && p.file.lists.length) dv.list(p.file.lists.slice(0, 5).map(l => l.text))
else dv.paragraph("_(no log entries)_")- h06 log
- strc
- h06
- 2026-08-21 re-rank: tier B held, all scores held. Moderna INTerpath-001 assessed and explicitly does NOT move this hypothesis; no new hypothesis warranted. → STRC Program Re-Rank 2026-08-21
- Cure-route audit (mRNA vs de-novo binder): B held; mech 2 / deliv 2 / misha_fit 2 unchanged. Hill K_M / n / max_boost re-confirmed NOT-MEASURED (tagged CIRCULAR FIT in source). 20% OHC LNP re-confirmed ASPIRATIONAL. Clearing threshold_fold 2.0 needs eff~0.50 (base) or ~0.25 (grid corner) vs realistic 0.01-0.03 — both are model contours, not measured requirements. → STRC Cure-Route Audit 2026-08-20
Connections
[part-of]STRC Hypothesis Ranking[see-also]STRC mRNA Therapy Hypothesis