PubMed / PMC
NCBI’s biomedical literature database. 36M+ citations. PMC provides full-text open access articles.
What it does
- Search biomedical literature (abstracts and full text)
- MeSH term-based precision search
- Citation tracking and related articles
- PMC: full-text open access papers
- E-utilities API for programmatic access
How to use
Web
- PubMed: https://pubmed.ncbi.nlm.nih.gov
- Search: “STRC hearing loss” or “stereocilin gene therapy”
API (E-utilities)
# Search
curl "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=STRC+hearing+loss&retmax=20&retmode=json"
# Fetch abstract
curl "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=PMID&retmode=xml"Python (Biopython)
from Bio import Entrez, Medline
Entrez.email = "[email protected]"
handle = Entrez.esearch(db="pubmed", term="STRC gene therapy", retmax=20)
results = Entrez.read(handle)
print(f"Results: {results['Count']}")Verified Status
VERIFIED — 40 papers for ‘STRC stereocilin’ in PubMed (121 for ‘STRC hearing loss’). Key papers: Iranfar 2026 (dual AAV), Verpy 2001 (discovery), Vona 2015 (deletions). Recent PMIDs: 41884524, 41562875, 41508981.
STRC usage
- All source notes in Brain reference PubMed papers
- 40 papers for ‘STRC stereocilin’, 121 for ‘STRC hearing loss’
- Key for E1659A: Iranfar 2026 (STRC dual AAV in mice), Verpy 2001 (STRC discovery), Vona 2015 (STRC deletions)
- STRC Gene Therapy Landscape 2026 — literature monitoring
- 2026-08-21, h03 delivery provenance (tier A → S). PMC open-access full text closed the
Anc80L65 provenance gap the 2026-08-20 cure-route audit filed. Two
sources/lit/notes created directly from PMC full text: 2017-landegger-anc80l65-inner-ear-nbt (PMC5340646, the P1-mouse 60-100% OHC figure the vault had quoted for a year with no note behind it) and 2022-andres-mateos-anc80l65-nhp-cochlear-transfer (PMC8924271, the primate test of the same vector and route: four transduced OHCs). Both are cited in the h03 re-ranking.
Next Steps
- Set up PubMed email alerts for “STRC” OR “stereocilin” — should be done
- Citation network mapping — identify key research clusters
- Pre-print monitoring — bioRxiv/medRxiv for STRC pre-prints
Connections
- ClinicalTrials.gov [see-also] — trial publications
- STRC Gene Therapy Landscape 2026 [used-in]
- OMIM [see-also] — curated literature
[part-of]Tools index