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Tag: off-target
6 items with this tag.
Apr 26, 2026
Phase 7I — APBS off-target rescore (CONHOH lead vs CONHOMe Tier-1)
h01
apbs
off-target
selectivity
head-swap
CONHOH
CONHOMe
Apr 26, 2026
Phase 8h-lite #3 · Off-target selectivity charge proxy (inconclusive light)
strc
h01
off-target
selectivity
electrostatics
Apr 26, 2026
STRC h01 Phase 5m TRPM4 Cross-Target tauRAMD 2026-04-26
strc
h01
phase-proof
phase5m
taramd
trpm4
off-target
kinetic-selectivity
pharmacochaperone
tier0
Apr 26, 2026
Hydroxamic Acid Divalent Cation Liability
strc
h01
chemotype
off-target
selectivity
Apr 24, 2026
STRC h01 Phase 6c hERG Extension 2026-04-24
strc
h01
phase-proof
phase6c
hERG
cardiac-safety
selectivity
off-target
Apr 23, 2026
Paralog Off-Target Rule
genetics
therapy-design
off-target
paralog
aso
crispr
prime-editing
rnai
specificity