DUET

Integrates mCSM and SDM into a consensus prediction of protein stability upon mutation.

Key Info

• URL: https://biosig.lab.uq.edu.au/duet/
• Category: Protein Structure
• API: Yes
• Free: Free
• ACMG Relevance: PP3
• Link Status: Unchecked

Why It Matters

Leverages support vector machines to combine graph-based signatures with empirical force fields for higher accuracy.

STRC Research Usage

Not yet tested on E1659A.

Next Steps

• Verify URL accessibility
• Test with STRC E1659A variant if applicable
• Document specific results

Connections

• STRC Variant c.4976A>C — Misha [see-also]
• STRC Gene [about]