FATHMM-MKL

Integrates multiple kernel learning to predict the functional consequences of SNVs.

Key Info

• URL: http://fathmm.biocompute.org.uk/
• Category: VEP
• API: Yes
• Free: Free
• ACMG Relevance: PP3
• Link Status: Unchecked

Why It Matters

Combines sequence conservation with genomic annotations to effectively score both coding and non-coding variations.

STRC Research Usage

Not yet tested on E1659A.

Next Steps

• Verify URL accessibility
• Test with STRC E1659A variant if applicable
• Document specific results

Connections

• STRC Variant c.4976A>C — Misha [see-also]
• STRC Gene [about]