RegulomeDB

Identifies functional DNA features and regulatory elements in non-coding genomic regions.

Key Info

• URL: https://regulomedb.org/
• Category: Regulatory
• API: Yes
• Free: Free
• ACMG Relevance: PP3

Why It Matters

Synthesizes massive datasets (ChIP-seq, ATAC-seq) to prioritize causal GWAS SNPs hiding within large linkage disequilibrium blocks.

How to Use

See https://regulomedb.org/ for documentation and access.

STRC Research Usage

VERIFIED — No known regulatory variants at E1659A position. Consistent with this being a coding variant, not regulatory.

Next Steps

• Test with STRC E1659A variant
• Verify API access
• Document specific results

Connections

• STRC Variant c.4976A>C — Misha [see-also]
• STRC Gene [about]