gEAR

Gene Expression Analysis Resource for comparing in vivo cochlear data to in vitro organoids.

Key Info

• URL: https://umgear.org/
• Category: Hearing Loss
• API: Yes
• Free: Free
• ACMG Relevance: N/A

Why It Matters

Identifies critical transcriptomic divergences in otic lineage cells, serving as the benchmark for validating inner ear organoid disease models.

How to Use

See https://umgear.org/ for documentation and access.

STRC Research Usage

PARTIAL — API endpoint returned 404. Web interface at umgear.org has cochlear gene expression data. STRC is highly expressed in outer hair cells — would provide tissue context.

Next Steps

• Test with STRC E1659A variant
• Verify API access
• Document specific results

Connections

• STRC Variant c.4976A>C — Misha [see-also]
• STRC Gene [about]