STRC Research

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Folder: sources/lit

124 items under this folder.

May 04, 2026
Localized active transport shapes the nanoscopic features at the tip of mechanosensory cilia
May 01, 2026
Pharmacological Correction of Aberrant DSCAML1 Localization by 4-Phenylbutyrate Ameliorates Epileptic Phenotypes in a Mouse Model Harboring the Patient-Specific A2105T Mutation
May 01, 2026
Targeting Alpha-Synuclein Aggregation With Chemical Chaperone IP-045: An Approach to Parkinson's Disease Therapy
Apr 25, 2026
1997-owens-pde4a-kinetics
- strc
- h05
- paper
- pde4
- camp
- kinetics
- cAMP
Apr 25, 2026
1998-lumpkin-hudspeth-stereocilia-calcium-regulation
Apr 25, 2026
1998-santalucia-unified-nearest-neighbor-dna
Apr 25, 2026
1998-yamoah-pmca-stereocilia-extrusion
Apr 25, 2026
2003-houslay-adams-pde4-review
- strc
- h05
- paper
- pde4
- camp
- kinetics
- cAMP
Apr 25, 2026
2004-matsuda-prestin-n-glycosylation
Apr 25, 2026
2005-hackney-calcium-buffering-proteins
Apr 25, 2026
2007-chipot-free-energy-calculations-book
- strc
- paper
- free-energy
- md
- fep
- ti
- abf
- mm-pbsa
- lra
- pka
- methods
Apr 25, 2026
2009-halgren-sitemap-druggability
Apr 25, 2026
2010-beurg-calcium-balance-ohc
Apr 25, 2026
2010-rajagopalan-prestin-glycosylation-jaro
Apr 25, 2026
2011-chao-camkii-holoenzyme-structure
Apr 25, 2026
2011-schwanhauser-mammalian-gene-expression-control
Apr 25, 2026
2012-zakeri-spycatcher-spytag-pnas
Apr 25, 2026
2012-zhang-stereocilia-protein-turnover
Apr 25, 2026
2014-schneider-de-novo-molecular-design-book
Apr 25, 2026
2015-genheden-ryde-mmpbsa-mmpgbsa-review
Apr 25, 2026
2019-anzalone-prime-editing-nature
Apr 25, 2026
2021-eberhardt-autodock-vina-1-2
Apr 25, 2026
2021-shubina-oleinik-strc-dual-aav-dfnb16
Apr 25, 2026
2022-zhi-dual-aav-split-pe-retina
Apr 25, 2026
2024-chen-acbe-adenine-transversion-editor
Apr 25, 2026
2024-davis-dual-aav-split-prime-editor-brain
Apr 25, 2026
2024-hartig-stereocilia-elongation-protein-stability
Apr 25, 2026
2025-roman-prime-editing-rbm20-cardiomyocytes
Apr 25, 2026
2025-wang-abe-pou4f3-dfna15-anc80l65
Apr 25, 2026
2026-04-25-ashmore-1987-ohc-electromotility-jphysiol
Apr 25, 2026
2026-04-25-gao-2014-organ-corti-oct-vibration
Apr 25, 2026
2026-04-25-gavara-2009-tm-collagen-anisotropy-afm
Apr 25, 2026
2026-04-25-gentet-2000-specific-membrane-capacitance-neurons
Apr 25, 2026
2026-04-25-ghaffari-2007-tm-traveling-wave-pnas
Apr 25, 2026
2026-04-25-gueta-2008-tm-anisotropy-stereocilia-deflection
Apr 25, 2026
2026-04-25-hu-2021-pvdftrfe-insitu-poling-frontiers-energy
Apr 25, 2026
2026-04-25-masaki-2009-tm-col11a2-anisotropy
Apr 25, 2026
2026-04-25-ren-2002-bm-traveling-wave-pnas
Apr 25, 2026
2026-04-25-santos-sacchi-1991-prestin-nlc-voltage
Apr 25, 2026
2026-04-25-shoelson-2004-tm-elasticity-inhomogeneity-biophysj
Apr 25, 2026
2026-04-25-teudt-2014-tm-bm-stiffness-cba-mouse
Apr 25, 2026
2026-sun-rbm24-alternative-splicing-cochlear
Apr 25, 2026
Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bu
Apr 25, 2026
Single-cell proteomics reveals changes in expression during hair-cell developmen
Apr 25, 2026
STRC Literature Log
Apr 24, 2026
1981-jencks-binding-energies-additivity-pnas
Apr 24, 2026
1998-kramer-karpen-polymer-ligand-dimers-nature
Apr 24, 2026
1998-mammen-polyvalent-interactions-angew
Apr 24, 2026
2014-choi-wpre3-aav-expression-cassette
Apr 24, 2026
2024-hu-myo15-promoter-engineering
- strc
- paper
- aav
- myo15
- promoter
- hair-cell
- h03
- ohc
- dfnb9
Apr 24, 2026
2024-lv-aav1-otof-lancet-trial
Apr 24, 2026
2025-zhao-arbiter-b8-enhancer-ohc
- strc
- paper
- aav
- enhancer
- ohc
- b8
- arbiter
- slc26a5
- prestin
- h03
Apr 23, 2026
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
Apr 23, 2026
Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B
Apr 23, 2026
Calcium oscillations increase the efficiency and specificity of gene expression
Apr 23, 2026
A large-conductance calcium-selective mechanotransducer channel in mammalian cochlear hair cells
Apr 23, 2026
Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains
Apr 23, 2026
Distinct mechanisms of calmodulin binding and regulation of adenylyl cyclases 1 and 8
Apr 23, 2026
The physiology of mechanoelectrical transduction channels in hearing
Apr 23, 2026
Actin-bound structures of Wiskott–Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
- strc
- paper
- actin
- wh2
- wasp
- biophysics
- h09
Apr 23, 2026
The WH2 Domain and Actin Nucleation: Necessary but Insufficient
Apr 23, 2026
Multifunctionality of the β-thymosin/WH2 module: G-actin sequestration, actin filament growth, nucleation, and severing
Apr 23, 2026
Single-cell proteomics reveals changes in expression during hair-cell development
Apr 23, 2026
Rate constants for the reactions of ATP- and ADP-actin with the ends of actin filaments
Apr 23, 2026
Actin and Actin-Binding Proteins
Apr 23, 2026
The organization of actin filaments in the stereocilia of cochlear hair cells
Apr 23, 2026
Stiffness and tension gradients of the hair cell’s tip-link complex in the mammalian cochlea
Apr 22, 2026
Li 2019 — 4PBA protects OHC function in Cdh23 mice (Neuroreport)
Apr 22, 2026
Holt 2021 — Dual AAV STRC delivery rescues hearing in neonatal mice
Apr 22, 2026
GeneReviews — STRC-Related Hearing Loss (DFNB16)
Apr 22, 2026
DB-OTO CHORD Trial — AAV dual-vector OTOF gene therapy in children
Apr 22, 2026
Iranfar 2026 — Dual AAV STRC gene therapy restores hearing in DFNB16 mice
Apr 22, 2026
Multicentre gene therapy for OTOF-related deafness followed up to 2.5 years.
Apr 21, 2026
Alternative splicing of the Rbm24 gene is essential for cochlear hair cell stereocilia integrity and hearing function in mice
Apr 20, 2026
Noninvasive Focal Gene Delivery into the Cerebellum of Non-Human Primates using Focused Ultrasound
Apr 20, 2026
Guiding Peptide Kinetics via Collective-Variable Tuning of Free-Energy Barriers
Apr 17, 2026
Integrating Seed-Based Design with Ribosome Display for the Development of Nanobody-like Protein Scaffolds
Apr 17, 2026
LinkCraft: An interactive tool for the design of flexible linkers
Apr 16, 2026
Rapid customization of base editors via machine learning-powered combinatorial mutagenesis
Apr 15, 2026
Development of the fluorescent probe CenSpark for labeling centrioles and cilia
Apr 15, 2026
A tri-modal contrastive learning framework for protein representation learning
Apr 14, 2026
Gene Therapy for Infants and Children With Otoferlin-Related Auditory Neuropathy Spectrum Disorder
Apr 14, 2026
Generation of human induced pluripotent stem cell lines from a patient with OTOF-related deafness and a carrier relative
Apr 14, 2026
Enhanced Piezoelectric Effect in P(VDF-TrFE) through Synergistic Templating by PEDOT:PSS and Paper
Apr 13, 2026
Multicolored, Sonosensitizer-Optimized Organic Mechanoluminescent Nanoparticles for Functional Sono-Optogenetics
Apr 13, 2026
Multicolored, Sonosensitizer-Optimized Organic Mechanoluminescent Nanoparticles for Functional Sono-Optogenetics
Apr 11, 2026
Combined Docetaxel-Loaded Perfluorocarbon Nanodroplets with Ultrasound-Mediated Blood-Brain Barrier Disruption for Effective Glioblastoma Treatment in Mice Model
Apr 08, 2026
Focused ultrasound mediated gene therapy for glioblastoma: A preclinical in vivo systematic review and meta-analysis
Apr 07, 2026
2026-04-07-chen-liheng-strc-reply
Apr 02, 2026
A near-infrared regulated programmable multi-mode periosteum scaffold for sequential healing of infected bone defects
Apr 01, 2026
Deep Learning-Enabled Engineering of a Hyper-Stable and Soluble MPB70-83 Antigen for Sensitive Bovine Tuberculosis Surveillance
Apr 01, 2026
Sensing of shear stress in vascular endothelial cells - from physiology to pathology
Mar 31, 2026
TMEM145 is a principal component of outer hair cell stereocilia
Mar 29, 2026
Cilia Dynamics in Primary Ciliary Dyskinesia: A Biophysical Characterization of the RSPH4A Founder Variant
Mar 27, 2026
Mechanical confinement balances ECM remodeling in chondrocytes via MAPK and Hedgehog signaling
Mar 22, 2026
2026-02-07-strc-diagnosis-vus-guide-RU
Mar 22, 2026
2026-02-07-strc-hearing-loss-treatment-RU
Mar 18, 2026
Duan_2018_micro_dystrophin_AAV
Mar 18, 2026
Gadenstaetter_2024_inner_ear_gene_therapy_review
Mar 18, 2026
Mendell_2020_micro_dystrophin_clinical
Mar 18, 2026
Omichi_2020_AAV_hair_cell_transduction
Mar 18, 2026
Verpy_2008_Stereocilin_Nature
Mar 04, 2026
Cryo-EM reveals a right-handed double-helix dimer architecture of PCDH15 critical for mechanotransduction
Feb 17, 2026
Postnatal Slc26a4 gene therapy improves hearing and structural integrity in a hereditary hearing loss model
Feb 07, 2026
2026-02-07-strc-diagnosis-vus-guide
Feb 07, 2026
2026-02-07-strc-hearing-loss-treatment
Feb 07, 2026
2026-02-07-strc-practical-guide-hk
Feb 07, 2026
STRC Gene Hearing Loss: Comprehensive Guide for Families
Dec 17, 2021
Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss
Sep 27, 2021
Cochlear Size Assessment Predicts Scala Tympani Volume and Electrode Insertion Force — Implications in Robotic Assisted Cochlear Implant Surgery
Jun 01, 2021
Clinical Use of the Self-Assembling Peptide RADA16: A Review of Current and Future Trends in Biomedicine
Apr 01, 2019
Stiffness and tension gradients of the hair cell's tip-link complex in the mammalian cochlea
Feb 20, 2019
Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics
Mar 01, 2018
Pharmacokinetic principles in the inner ear: Influence of drug properties on intratympanic applications
Oct 01, 2016
Human Cochlear Hydrodynamics: A High-Resolution μCT-Based Finite Element Study
Aug 01, 2015
Perilymph Kinetics of FITC-Dextran Reveals Homeostasis Dominated by the Cochlear Aqueduct and Cerebrospinal Fluid
Mar 01, 2011
Stereocilin connects outer-hair-cell stereocilia to one another and to the tectorial membrane
Apr 01, 2009
Proteomics Analysis of Perilymph and Cerebrospinal Fluid in Mouse
Jun 14, 2005
Dynamic reassembly of peptide RADA16 nanofiber scaffold
Oct 01, 2003
Fabrication of novel biomaterials through molecular self-assembly
Nov 23, 2001
Self-assembly and mineralization of peptide-amphiphile nanofibers
Apr 01, 2001
Quantification of solute entry into cochlear perilymph through the round window membrane
Jun 06, 2000
Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds
Apr 15, 1993
Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane

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